One of the major challenges faced by Western countries and the world as a whole after the financial crisis of 2007 and the following stagnation is to find new thinking patterns for economic growth and innovation. Recent research depicts economic growth as an evolutionary process occurring in out-of-equilibrium ecosystems involving technologies and industrial capabilities. In order to properly address the challenges posed by such complex ecosystems new theories are required. We aim to contribute to such a paradigmatic shift from a multidisciplinary point of view, developing innovative and effective metrics and forecasting methods, as well as new conceptual schemes for modelling the complexity of the economic world.